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StemVac

Innovative immunotherapy approaches to treat breast cancer patients Breast cancer is the most common malignancy in women and is the second leading cause of cancer deaths (after lung cancer). There is a clear medical need for more efficient breast cancer treatments in terms of distant recurrence and safety and tolerance....
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BENEFIT

The treatment of patients in clinical practice relies on the results of randomized clinical trials. The statistical methods currently used to test the treatment effects in such trials take into account a single criterion called "primary endpoint". This is an incomplete assessment of trial results, especially in oncology and chronic...
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iCone

Human iPSC-derived Cortical Neurons for Research and Development. The project aims to make highly functional human cortical neurons from stem cells. Right now these cellular models, in combination with laboratory tests, provide a unique and novel platform bridging traditional laboratory tests and clinical testing in patients. Showing close resemblance to...
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Single Cells

Development of an innovative approach for the control of microbial subpopulation in bioprocesses. Wagralim R&I project, co-led by BioWin. Microbial populations, even those called clonal (genetically identical), are inherently heterogeneous. In the biotechnology industry, this heterogeneity affects the performance and reproducibility of bioprocesses based on the use of microorganisms. In...
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Inteliphages

Development of a powerful therapy to fight antimicrobial resistance. The aim of the Inteliphages project is to develop dried and encapsulated phages in order to treat bacterial infections that are either resistant to antibiotics or for which antibiotics are not indicated for other reasons. The development of dried and encapsulated...
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AERONEXT

Asthma and COPD (Chronic Obstructive Pulmonary Disease) are amongst the most common causes of mortality and morbidity worldwide, representing together the third largest medical market. Their prevalence is increasing due to the global industrial pollution. Inhaled therapies, the preferred treatment options, are made of a drug combined with a medical...
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FAR

When surgical removal is not possible, oncologists have few treatment options to offer their cancer patients. Trasis, Xpress Biologics, CMMI (ULB) and UMONS are embarking on the FAR (Fragments of Antibodies for Radioimmunotherapy) research project to promote the use of antibody fragments as carriers of radioactive isotopes. By using both the ability of antibody fragments to target tumours and...
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BoneRec

The BoneRec project aims to develop a new tissue-engineered product indicated for bone reconstruction. This ideal bone graft substitute will be biomechanically stable, resorbable and will have osteoconductive, osteogenic and osteoinductive properties. The biomechanical property will be provided by Cerhum's ceramic graft (coordinating company of the project) and the osteoconductive,...
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M2-TARGET

M2-Target aims to develop a non-invasive imaging method for the detection and quantification of M2 macrophages. This method is based on a new radiotracer (called 68Ga-ABSCINT-206) initially developed at the Vrije Universiteit Brussel (VUB). It is composed of a single-domain antibody fragment (also called "nanobodies") that recognizes a receptor (CD206)...
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