Human iPSC-derived Cortical Neurons for Research and Development.
The project aims to make highly functional human cortical neurons from stem cells. Right now these cellular models, in combination with laboratory tests, provide a unique and novel platform bridging traditional laboratory tests and clinical testing in patients. Showing close resemblance to the human brain, these tests have the potential to accelerate therapeutic drug discovery, lower the expenses of development, and in addition, reduce the need for laboratory animals. As a next step, the consortium will develop quality-controlled processes in large quantities using good manufacturing principles. This key step opens the door to cellular therapy in the near-term future.
Companies: Catalent, NCardia
Universities: ULB, ULg