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Development of inhaled synergetic combinations for the treatment of resistant respiratory infections The aim of BioFiNa is to develop inhaled synergetic combinations for the treatment of resistant respiratory infections. The development of germs which are increasingly resistant to antibiotics is a major public health problem. The arsenal of available antibacterials...
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Development and validation of new molecules to restore the immune response against cancer cells Immunotherapy, based on therapeutic vaccination against antigens expressed by cancer cells, is at the present time a very promising approach. Its application is limited, however, due to mechanisms of immune suppression that are critical to control...
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Discovery of new targets for the treatment of Parkinson’s disease The HOPE 4 PD project aims to validate two G protein coupled receptors (GPCRs), whose expression is altered in the striatum of patients with Parkinson's disease, as targets of drugs to treat neuro-degenerative diseases, Parkinson's disease being the first indication....
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Assembly of an artificial ovary combining isolated human ovarian follicles, fibrin and a textile pocket The objective of this project is to develop a 3D biodegradable matrix to graft an autologous ovarian tissue or isolated follicles in patients with impaired fertility following a gonadotoxic treatment. This biofunctional fibrin-based matrix will...
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Statistical Monitoring Applied to Research Trials While the detection of deliberate (fraud) or unintentional errors concern pharmaceutical and biotechnology companies enormously, there is currently no integrated and automated system to monitor the quality of data based on statistical tests and artificial intelligence or data mining. IDDI is a pioneer in...
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Glaucoma Management Implant System Research on a next generation Glaucoma Management Implant System that incorporates the latest advances in biomaterials, MEMS sensor and electronics technologies. The goal of the implant system is to provide a novel combination of therapeutic and diagnostic benefits for glaucoma patients and caregivers, while significantly reducing...
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Innovative immunotherapy approaches to treat breast cancer patients Breast cancer is the most common malignancy in women and is the second leading cause of cancer deaths (after lung cancer). There is a clear medical need for more efficient breast cancer treatments in terms of distant recurrence and safety and tolerance....
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