Biopharmacy

Chitosan-based Targeting Drug Delivery Systems (Cs-tDDS) and their Proof of Concept Today, the most efficient therapeutic approaches in cancer rely on targeting the tumoral cells in order to enhance the therapeutic effect of the drug, to decrease its dosage and to limit its side effects. The TARGETUM Project aims at...

Development of new cell-based in vitro models for ADME/Toxicity screening, based on human adult progenitor/stem cells Characterization of a new drug candidate during preclinical evaluation includes, in addition to potency and safety an assessment of drug metabolism and pharmacokinetics. Drug metabolism studies require identification ofthe products of drug candidate metabolism,...

Holographic Analyses Devices The objective of the BioLine project is to further validate and optimize Ovizio’s technology for cell culture monitoring allowing it to analyze in a non invasive and reliable way, key cell culture parameters like cell numbers, cell morphology, viability, distribution of cell sizes and the presence of...

Development and production of DNA vaccines without antibiotic resistance gene DNA vaccination seems to be a promising method of fighting diseases. For this application, plasmid DNA is injected into the subject (man or animal). This plasmid DNA encodes for an antigen that will be produced by the subject’s cells. In...

The health sector sees the emergence of new generations of innovative therapies, among which promising approaches are related to gene and cell therapies. This evolution often leads to the deployment of patient-centric processes, implying not only dramatic changes in the bio-production processes but also significant increases of the treatment costs....